Causes Keratoconus has been associated with a variety of causes e.g.: Heredity Environment – more prevalent in hot, dry climates Atopic diseases with their associated conditions (asthma, hayfever, eczema, allergies) Oxidative stress – inability to eliminate/neutralize harmful free radicals which weakens the collagen and thins in cornea Endocrine system – strong association with puberty Eye rubbing – due to itchy eyes What is keratoconus? Prevalence How does it affect the patient? Treatment